Searchable abstracts of presentations at key conferences in endocrinology

ea0057012 | Immune checkpoint inhibitors and type 1 diabetes mellitus: a case report and systematic review of the literature | BES2018

Immune checkpoint inhibitors and type 1 diabetes mellitus: a case report and systematic review of the literature

de Filette Jeroen MK , Joeri Pen , Brigitte Velkeniers , Kharagjitsingh Aan V

Introduction: Immune checkpoint inhibitors have revolutionized the treatment of advanced malignancies. These monoclonal antibodies target cytotoxic T-lymphocyte antigen-4 (CTLA-4), programmed cell death 1 (PD-1) or its ligand (PD-L1). Endocrine side effects are common, and while hypophysitis and thyroid disorders are predominant, checkpoint-blockade associated diabetes mellitus deserves further notice.Methods: We present the case of a 61-year old male wi...

ea0079019 | Abstracts | BES2021

COVID-19 & Cushing’s disease in a patient with ACTH-secreting pituitary carcinoma

Jeroen M.K. de Filette , Bastiaan Sol , Gil Awada , Corina E. Andreescu , David Unuane , Duc Nam Nguyen , Sandrine Aspeslagh , Jan Poelaert , Brigitte Velkeniers , Bert Bravenboer

Background : The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of an unprecedented scale, with an ever-growing impact on healthcare systems. The clinical presentation of coronavirus disease 2019 (COVID-19) is diverse, ranging from asymptomatic illness to respiratory failure requiring admission to the intensive care unit (ICU). Risk factors for severe presentation include old age, male gender, underlying comorbidities such as metabolic syndr...